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. Author manuscript; available in PMC: 2008 Dec 1.
Published in final edited form as: Exp Mol Pathol. 2007 Sep 26;83(3):301–310. doi: 10.1016/j.yexmp.2007.08.020

Figure 4. Airspace enlargement is attenuated in Cd8-deficient mice exposed to acrolein.

Figure 4

(A) Sham-exposed wild-type mice (B) Sham-exposed Cd8(−/−) mice (C) acrolein-exposed (12 weeks) wild-type mice (D) acrolein-exposed (12 weeks) Cd8(−/−) mice. Photomicrographs (400x original magnification) are representative of 8 mice per group. Scale bar = 100μm. (E) Mean linear intercept (Lm) was calculated from photomicrographs of lung parenchyma of sham- and acrolein-exposed (12 weeks) wild-type and Cd8(−/−) mice. Lm values presented are means ± sem. No significant differences were observed between sham-exposed wild-type and Cd8(−/−) mice. * denotes value significantly greater than strain-matched sham-exposed control at p<0.05. # denotes significantly different from wild-type mice exposed to acrolein at p<0.05.