Table 2.
Binding affinities (M−1) for parent polyamides 3 and 7 on plasmid pMFST5. Equilibrium association constants reported are mean values from three DNase I footprinting titration experiments. Standard deviations are shown in parentheses.
Polyamide | M | O | S |
---|---|---|---|
3 | 9.8(± 1.3) × 109 | 4.7(± 1.3) × 109 | -- |
7 | 7.0(± 1.0) × 108 | 5.9(± 2.1) × 108 | 1.3(± 0.2) × 109 |