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The current view on the different associations of Hat1p within the cell. In addition to the cytoplasmic Hat1p/Hat2p complex, the Hat1p/Hat2p-Hif1p chromatin assembly complex is recruited to chromatin during S-phase. A minor fraction of Hat1p/Hat2p is constitutively associated with ORC and presumably chromatin-bound. Additional H3-specific acetylation and additional substrates for Hat1p are possible.
