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The C termini of five EPH-related RTKs bind to the PDZ domain of AF6
| RTK | Accession no. | Analyzed C terminus | AF6 binding |
|---|---|---|---|
| EphB2 | L36643 | IQSVEV | + |
| EphB6 | L77867 | PGSVEV | + |
| EphB5 | L23783 | LEPVEV | + |
| EphB3 | X75208 | TLPVQV | + |
| EphA3 | M83941 | NGPVPV | − |
| EphA4 | L36654 | GRMVPV | − |
| EphA7 | L36642 | GTGIQV | + |
| EphA6 | U58332 | EKGFHV | − |
| EphA2 | M59371 | TVGIPI | − |
| Nsk2 | X86445 | EGTVGV | − |
LexA peptide fusions derived from the C termini of various RTKs were coexpressed with the PDZ domain in S. cerevisiae L40.
