Table 1.

Inhibition of nuclear translocation of angiogenin

Inhibitor	Nuclear 125I-angiogenin, cpm	% inhibition
Control	3,090  ±  260	0
Genistein (100 μM)	3,300  ±  170	0
Oxophenylarsine (10 μM)	3,040  ±  70	0
Staurosporine (100 nM)	2,710  ±  70	12
Neomycin (100 μM)	1,230  ±  60	60
U-73122 (10 μM)	2,140  ±  30	31
U-73343 (10 μM)	2,890  ±  100	6

HUVE cells, 50,000 per 35-mm dish, were treated with inhibitors at 37°C for 30 min. ¹²⁵I-angiogenin was added to a final concentration of 1 μg/ml and incubated at 37°C for 30 min. Nuclear fractions were isolated and radioactivities were determined.