Table 7.
Mean±SEM values of total numbers of NeuN-positive, NeuN-negative and all cells in the P21 caudate-putamen and frontal cortex estimated by stereology. Cell numbers were estimated separately for the upper (II–III) and lower (V–VI) layers of the frontal agranular cortex. ANOVA showed that the differences among the 3 groups were not statistically significant (p>0.05). Since ANOVA did not reveal significant differences, Tukey’s Multiple Comparison Test was not performed.
| Caudate-Putamen (105) | |||
|---|---|---|---|
| L-DOPA | ASC | WATER | |
| NeuN-positive | 8.0±0.4 | 7.7±0.5 | 8.1±0.2 |
| NeuN-negative | 7.7±0.2 | 6.4±0.3 | 7.0±0.4 |
| Total cells | 16.0±0.5 | 14.0±0.7 | 15.0±0.4 |
| Frontal Cortex All layers (105) | |||
| L-DOPA | ASC | WATER | |
| NeuN-positive | 2.5 ± 0.1 | 2.6 ± 0.2 | 2.9 ± 0.2 |
| NeuN-negative | 2.3 ± 0.1 | 2.2 ± 0.1 | 2.6 ± 0.1 |
| Total cells | 4.9 ± 0.2 | 4.9 ± 0.2 | 5.5 ± 0.3 |
| Frontal Cortex Layers II–III (105) | |||
| L-DOPA | ASC | WATER | |
| NeuN-positive | 1.5 ± 0.7 | 1.5 ± 0.1 | 1.7 ± 0.1 |
| NeuN-negative | 1.3 ± 0.6 | 1.3 ± 0.1 | 1.4 ± 0.1 |
| Total cells | 2.8 ± 0.1 | 2.8 ± 0.2 | 3.1 ± 0.2 |
| Frontal Cortex Layers V–VI (105) | |||
| L-DOPA | ASC | WATER | |
| NeuN-positive | 1.1 ± 0.1 | 1.1 ± 0.1 | 1.3 ± 0.1 |
| NeuN-negative | 1.0 ± 0.1 | 0.9 ± 0.1 | 1.2 ± 0.1 |
| Total cells | 2.1 ± 0.1 | 2.1 ± 0.1 | 2.5 ± 0.2 |