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. 1997 Aug 11;138(3):615–628. doi: 10.1083/jcb.138.3.615

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Disruption of poles by antidynein antibodies. The monoclonal antibody (mAb 70.1) that recognizes the intermediate chain of cytoplasmic dynein was added to extracts containing chromatin bead spindles (A), DMSO asters (B), or sperm DNA spindles (C) with centrosomes. Pole structures were disrupted within 10 min. Bar, 5 μm.