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. 1997 Aug 11;138(3):589–603. doi: 10.1083/jcb.138.3.589

Figure 2.

Figure 2

Figure 2

MBC sequence and alignment with human DOCK180 as well as related open reading frames. The alignment was done using Clustal W and presented using Boxshade. Black boxes indicate amino acid identity, while gray boxes indicate amino acid similarity to MBC. Arrowheads highlight mutations found in mbc alleles. The consensus Crk-binding sites (PPxLPxK) of DOCK180 are underlined. A potential Crk-binding site in MBC is noted with dots. Stars mark essential SH3 consensus residues (Musacchio et al., 1994). The GenBank/EMBL/DDBJ accession numbers are D86964 for the myeloblast-specific cDNA KIAA0209, Z81032 and Z81054 for the C. elegans ORFs, and AA110899 for the mouse expressed sequence tag. mbc sequence data are available from GenBank/EMBL/DDBJ under accession number AF007805.