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. 1997 Aug 11;138(3):697–706. doi: 10.1083/jcb.138.3.697

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Spontaneous formation of multinucleated giant cells in monolayers of P2Zhyper cells and HEK293 cells transfected with the P2X₇ receptor. Cells were plated at the concentration of 5 × 10⁵ cells/ml and grown for 3 d. (A–C) P2Zhyper macrophages; (D) HEK293 cells stably transfected with the P2X₇ receptor. Photographs were taken with a 20× objective in A and a 40× objective in B–D. Bars: (A) 50 μm; (B–D) 25 μm.