Table II.

Proportion (%) of Apoptotic Cells That Stain Positive for Oligodendrocyte-specific Markers by Immunofluorescence

Oligodendrocyte- specific antigen		No. of mice		No. of apoptotic cells counted		Antigen-positive cells (%)
PLP		3		183		75 ± 0.5
O4		3		110		83 ± 4
Ranscht		3		176		83 ± 3
MBP		3		134		43 ± 8
PDGFαR		2		353		8 ± 0.5

Oligodendrocyte-specific antigen-positive/TdT-positive/DAPI-positive cells were located in the hypothalamus, pons, medulla, and cervical spinal cord. Counts are presented as mean ± SEM and were obtained from 10-μm sagittal cryostat sections of brain from two or three p18 msd mice.