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. 2007 Nov 14;104(47):18654–18659. doi: 10.1073/pnas.0704652104

Fig. 3.

Fig. 3.

Comparison of the genetic alterations among the three clusters. Each cluster corresponds to very distinct genetic profiles. CIMP1 is characterized by high frequency of MSI (80%) and BRAF mutations (53%), CIMP2 is characterized by a higher rate of KRAS mutations (92%), and CIMP negative is characterized by high frequency of p53 mutations (71%).