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. 2007 Nov 19;104(48):18913–18918. doi: 10.1073/pnas.0706114104

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© 2007 by The National Academy of Sciences of the USA

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Fig. 1. — Graphical illustration of vesicles being tethered to a supported bilayer and subsequent DNA-mediated docking between tethered vesicles. (A) Vesicles with a tethering DNA (sequence A) and docking DNA (sequence C or C′) are incubated with a supported bilayer that displays the complementary tethering DNA (sequence A′). (B) Hybridization of A and A′ tethers the vesicles to the supporting bilayer, and the vesicles are free to diffuse in the plane of the supported bilayer. Tethered vesicle diffusion and diffusion of the docking DNA on the vesicles' surfaces are illustrated with arrows. (C) Collisions between vesicles can lead to docking of tethered vesicles via hybridization of C and C′ DNA.