Fig. 2.

Bimodal stochastic solutions distinct from the unique deterministic solution. Histogram showing the bimodal distribution of the protected agonists at steady state (red) for a situation when there are 10 agonist (A₁) and 10 antagonists (A₂). The corresponding single steady state solution of the deterministic ODEs (blue) is also shown. The other parameter values are: k₁ = 1, k₂ = 1, k₃ = 100, k₄ = 1, k₅ = 100, k_D = 1 (all s⁻¹), and statistics were collected over 5,000 trajectories obtained by using the Gillespie algorithm. The result is robust to variations in the parameter values as long as there is strong feedback.