Table 3.

Compounds that increase long-lived protein degradation

Name	% of control long lived protein degradation
	1 h	2 h	4 h	24 h
Rapamycin	159.89 ± 11.46	171.67 ± 10.41	149.89 ± 24.83	165.87 ± 4.08
Fluspirilene	93.82 ± 3.25	143.17 ± 4.26	144.79 ± 9.02	145.50 ± 2.98
Trifluoperazine	76.62 ± 2.32	105.60 ± 5.01	109.00 ± 5.22	124.78 ± 2.05
Pimozide	129.13 ± 11.46	155.80 ± 9.22	152.01 ± 9.63	162.47 ± 3.50
Nicardipine	84.62 ± 4.48	126.59 ± 3.83	122.60 ± 7.70	121.03 ± 13.43
Penitrem A	92.88 ± 2.83	126.09 ± 0.47	132.13 ± 10.01	141.83 ± 1.25
Niguldipine	71.65 ± 2.68	107.42 ± 2.72	105.68 ± 2.74	117.85 ± 1.98
Loperamide	78.70 ± 13.17	122.10 ± 6.48	125.21 ± 4.29	139.19 ± 18.77
Amiodarone	101.32 ± 5.95	122.42 ± 9.71	110.75 ± 3.68	116.73 ± 5.54

The rates of long-lived protein degradation were measured as described in Methods. The percentages of change were expressed by dividing the rate of degradation in compound-treated cells by that of DMSO-treated cells.