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The Journal of General Physiology logoLink to The Journal of General Physiology
. 1937 Sep 20;21(1):93–105. doi: 10.1085/jgp.21.1.93

VISUAL ADAPTATION AND CHEMISTRY OF THE RODS

George Wald 1, Anna-Betty Clark 1
PMCID: PMC2141927  PMID: 19873041

Abstract

1. The reality of a chemical cycle proposed to describe the rhodopsin system is tested with dark adaptation measurements. 2. The first few minutes of rod dark adaptation are rapid following short, slower following long irradiation. As dark adaptation proceeds, the slow process grows more prominent, and occupies completely the final stages of adaptation. 3. Light adaptation displays similar duality. As the exposure to light of constant intensity lengthens, the visual threshold rises, and independently the speed of dark adaptation decreases. 4. These results conform with predictions from the chemical equations.

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Selected References

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  1. Winsor C. P., Clark A. B. Dark Adaptation after Varying of Light Adaptation. Proc Natl Acad Sci U S A. 1936 Jun;22(6):400–404. doi: 10.1073/pnas.22.6.400. [DOI] [PMC free article] [PubMed] [Google Scholar]

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