Figure 2.

Deduced amino acid sequence of LdNT1.1 (Upper) compared with the human equilibrative nucleoside transporter (18) hENT1 (Bottom) using the pileup program (14) with a gap weight of 4 and a gap length weight of 3. Amino acids that are identical between the two sequences are shown in white over a black background. The solid lines over the LdNT1 sequence and under the hENT1 sequence designate the predicted (15) transmembrane domains of each protein. The asterisks designate amino acids that are different in LdNT1.2. The amino acids P43, M107, T160, A489, T490, Y491 in LdNT1.1 are S43, I107, A160, E489, R490, H491 in LdNT1.2.