Figure 3.

The genomic rearrangement is unique to C57BL/Wld^s. (a) A BamHI genomic Southern blot was hybridized with a probe located close to the proximal boundary, giving a C57BL/Wld^s-specific shifted band. (b) A BlpI Southern blot was hybridized with 269/L, located centrally within the repeat unit, and with 5P1 as a single-copy control. Closely related C57 strains are shown in a and a representative group of other strains in b. Additional strains tested and not shown were 129/J, AKR/J, BALB/cJ, BDP/J, BUB/BnJ, CAST/Ei, C3H, DBA, HRS/J, I/LnJ, LT/Sv-A<y>/A, MA/MyJ, and NZW/LacJ. In both assays, the Wld^s allele was unique.