Table 1.

Differences between the fragile X and non-fragile categories and between males and females, in ADOS major domain scores. Means and standard deviations (SD) for two major ADOS-G domain scores, and a summary score, in males and females separately and combined, in the premutation and full mutation groups, and non-fragile X normal controls.

	Controls			Premutation			Full mutation
Variable	N	Mean	SD	N	Mean	SD	N	Mean	SD
Language & Communication (COM)
Total	42	0.712	1.17	59	0.973	1.73	161	2.73	2.26
F	9	0.332	0.71	46	0.853	1.79	45	1.69*	2.45
M	33	0.822	1.26	13	1.383	1.50	116	3.13	2.05
Reciprocal Social Interaction (RSI)
Total	42	1.692	2.31	59	2.343	2.91	161	6.13	4.00
Females	9	1.112	1.36	46	1.703*	2.48	45	4.40*	4.40
Males	33	1.85 1,2	2.50	13	4.623	3.28	116	6.80	3.81
Communication & Social Interaction Total (CSIT)
Total	42	2.402	3.27	59	3.323	4.49	161	8.86	5.78
Females	9	1.442	1.94	46	2.573*	4.20	45	6.11*	6.04
Males	33	2.671,2	3.52	13	6.003	4.58	116	9.93	5.33

Significant differences (p-values < 0.05) between: normal vs premutation

¹normal vs full mutation

²premutation vs full mutation

³and females vs males within each group (*).