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. 1986 Apr;166(1):100–104. doi: 10.1128/jb.166.1.100-104.1986

F plasmid ccd mechanism in Escherichia coli.

S Hiraga, A Jaffé, T Ogura, H Mori, H Takahashi
PMCID: PMC214563  PMID: 3007430

Abstract

The ccd mechanism specified by the ccdA and ccdB genes of the mini-F plasmid determines fate of plasmid-free segregants in Escherichia coli (Jaffé et al., J. Bacteriol. 163:841-849, 1985). The killing function in plasmid-free segregants by the ccd mechanism did not affect cell growth of coexisting cells in the same culture. Elongated cells and anucleate cells caused by the ccd mechanism were clearly detected by flow cytometry in cultures of bacterial strains harboring Ccd+ Sop- mini-F plasmids defective in partitioning. This indicates that the defect in correct partitioning of plasmid DNA molecules into daughter cells also induces the ccd mechanism to operate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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