Figure 5. Sterile protection in [BALB/c×C57BL/6] F1 mice immunized three times with P. berghei or P. berghei [PfCS] and challenged with 5000 P. berghei or P. berghei [PfCS] sporozoites.

All animal groups (5 mice per group) were monitored for blood-stage infections by examination of Giemsa-stained blood smears obtained daily from day 2 to day 11 post-challenge. All naive control mice developed a patent blood-stage infection.