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. 1998 Aug 18;95(17):10123–10128. doi: 10.1073/pnas.95.17.10123

Figure 2.

Figure 2

Inhibitory effect of BO-653 on the atherosclerosis of WHHL rabbits. Male rabbits were maintained for 6 months on a diet containing the indicated concentration of the compound. (a) Representative photographs of aortic inner surfaces of WHHL rabbits. The aorta of a wild-type JW rabbit is presented as normal aortic inner surface. (b and c) Effect of BO-653 on intimal surface area with atherosclerotic lesions of aortic arch (b) and whole aorta (c). (d) Tissue concentrations of the compounds in WHHL rabbits treated for 6 months. All results are shown as mean ± SE. n = 4 or 5. ∗, P < 0.05; ∗∗, P < 0.01.