. Author manuscript; available in PMC: 2008 Dec 15.

Published in final edited form as: Bioorg Med Chem Lett. 2007 Oct 12;17(24):6879–6882. doi: 10.1016/j.bmcl.2007.10.015

Table 2.

Endothelial genes most distinctly regulated by the purified active compound (TDEYA; 5 μg/ml, 4 hours)

UniGene ID	Gene	Log ratio^a	Fold Change	Change^b	Change p-value^c
Hs.12813	TCDD-inducible poly(ADP-ribose) polymerase (TI-PARP)	1.2	2.3	I	0.00002
Hs.196384	Prostaglandin-endoperoxide synthase 2 (COX2)	1.0	2.0	I	0.00002
Hs.594481	Serpin peptidase inhibitor, clade B, member 2 (SerpinB2)	1.0	2.0	I	0.00002
Hs.154654	Cytochrome P450, family 1, subfamily B, polypeptide 1	2.7	6.5	I	0.00002
Hs.390594	Solute carrier family 7, member 11	1.2	2.3	I	0.00002
Hs.591945	Zinc finger and BTB domain containing 16	−1.0	−2.0	D	0.99992
Hs.124649	ATP-binding cassette, sub-family G, member 1	−0.9	−1.9	D	0.99995
Hs.651231	Heparan sulfate proteoglycan 2 (perlecan)	−0.8	−1.7	D	0.99996
Hs.170355	Mesenchyme homeobox 2	−1.1	−2.1	D	0.99997
Hs.468972	AT rich interactive domain 1A (SWI-like)	−0.9	−1.9	D	0.99998

^{a, b, and c}

Log ratio, Change, and Change p-value: explained under Table 1. The top five up and down regulated genes are shown (based on the Change p-value).

Bold: These genes were also seen in the list of the most distinctly regulated genes by TSS (Table 1).