Table 2.
Cardiorespiratory parameters measured in the four groups of piglets before death
| Cardiorespiratory parameters | Group | p value | |||
| Control | NVI | VNI | VI | ||
| Number of animals | 5 | 6 | 6 | 8 | |
| pH | 7.41 ± 0.04 | 7.38 ± 0.04 | 7.40 ± 0.27 | 7.40 ± 0.10 | 0.12 |
| PaO2/FiO2 (mm Hg) | 414 ± 82 | 385 ± 38 | 279 ± 130a | 208 ± 113b,c | <0.001 |
| PaCO2 (mm Hg) | 37 ± 6 | 41 ± 3 | 40 ± 7 | 44 ± 7 | 0.16 |
| Ppeak (cm H2O) | 19 ± 1 | NP | 28 ± 14 | 37 ± 14 | 0.05 |
| Pplat (cm H2O) | 15 ± 3 | NP | 20 ± 11 | 27 ± 10 | 0.07 |
| Crs (ml/cm H2O) | 25 ± 7 | NP | 20 ± 6 | 16 ± 6a | <0.05 |
| MAP (mmHg) | 116 ± 11 | 106 ± 11 | 92 ± 12a | 74 ± 24b,c | 0.001 |
ap < 0.05 versus control; bp < 0.01 versus control; cp < 0.05 versus NVI. Data are expressed as mean ± standard deviation. Crs, respiratory compliance; MAP, mean arterial pressure; NP, not performed; NVI, non-ventilated-inoculated piglets; PaCO2, arterial partial pressure of carbon dioxide; PaO2/FiO2, arterial partial pressure of oxygen/fraction of inspired oxygen; Ppeak, maximum peak airway pressure; Pplat, end-inspiratory plateau airway pressure; VI, ventilated-inoculated piglets; VNI, ventilated-non-inoculated piglets.