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. Author manuscript; available in PMC: 2008 Apr 25.
Published in final edited form as: Nature. 2007 Oct 25;449(7165):1073–1077. doi: 10.1038/nature06251

Figure 1. A genome-wide shRNA screen identifies factors required for Ras-mediated epigenetic silencing of Fas.

Figure 1

a, Schematic summary of the genome-wide shRNA screen for Ras-mediated epigenetic silencing of Fas. b, Immunoblot analysis monitoring Fas expression in the 28 K-ras NIH 3T3 knockdown (KD) cell lines. Expression of Fas in K-ras NIH 3T3 cells in the presence and absence of 5-aza-2’-deoxycytidine (5-aza) is also shown. K-Ras expression is shown as a loading control.