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. 2007 Nov;177(3):1725–1731. doi: 10.1534/genetics.106.069088

TABLE 1.

Parameter values for the simulation models

Target value Scaled value λ = 10
No. chromosomes, N 20,000 2000
No. generations 300,000 30,000
Mutation rate, μ 2.3 × 10−8 2.3 × 10−7
Crossover rate, Rc 1.1 × 10−8 1.1 × 10−7
Gene conversion rate, Rg 1.2 × 10−8 1.2 × 10−7
Directional selection
 Selection coefficient Inline graphic
 Dominance coefficient h = 0.5
Balancing selection
 Selection coefficient Inline graphic
 Dominance coefficient Inline graphic

The top section applies to all simulations. For both nonneutral models, the proportion of the genome under selection is 5 × 10−4 (i.e., PN = 0.9995). Inline graphic denotes the Gaussian (normal) distribution with mean μ and standard deviation σ.