TABLE 1.
Parameter values for the simulation models
Target value | Scaled value λ = 10 | |
---|---|---|
No. chromosomes, N | 20,000 | 2000 |
No. generations | 300,000 | 30,000 |
Mutation rate, μ | 2.3 × 10−8 | 2.3 × 10−7 |
Crossover rate, Rc | 1.1 × 10−8 | 1.1 × 10−7 |
Gene conversion rate, Rg | 1.2 × 10−8 | 1.2 × 10−7 |
Directional selection | ||
Selection coefficient | ![]() |
|
Dominance coefficient | h = 0.5 | |
Balancing selection | ||
Selection coefficient | ![]() |
|
Dominance coefficient | ![]() |
The top section applies to all simulations. For both nonneutral models, the proportion of the genome under selection is 5 × 10−4 (i.e., PN = 0.9995). denotes the Gaussian (normal) distribution with mean μ and standard deviation σ.