Fig. 1.

Molecular identification of the lesions in hoover(mef2ca) mutants. (A) Schematic showing the map position of hoover, which is non-recombinant with mef2ca in 1008 meioses. (B) mef2ca is mutated in all three hoover alleles. In b631 mutants, an A-to-C mutation is predicted to change the initiator methionine to leucine. In b1086 mutants, an A-to-T mutation creates an early stop in exon two, predicted to create a truncated protein lacking a MEF2 domain. In tn213 mutants, a T-to-C mutation alters the conserved second nucleotide of the intron 7 splice donor.