Scheme 4.
Synthesis of 3,4,5-Trichloro-2-thiopheneacid Chloride, 2. (a) 1. n-BuLi/MTBE, -60°C, 2. CO2; or 1. Mg/1,2-DBE/THF, 35°C, 2. CO2; (b) SOCl2, cat. DMF, 1,2-DCE, 80°C
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