Table I.

Quantitative Analysis of Pancreatic Development In Vitro

Experience		Average cell number/pancreatic rudiment						n
		Endocrine			Exocrine
A
Control		1,900 ± 100	NS		900 ± 80	NS		5
BB-3103		1,800 ± 90			836 ± 100			8
B
Control		1,900 ± 100	NS		940 ± 110	NS		10
TGF-β1		1,700 ± 80			1,150 ± 100			10
C
Control		1,800 ± 100	NS		1,000 ± 120	NS		11
Anti-TGF-β (d0–d7)		1,500 ± 200			1,400 ± 100			16
D
Control		1,600 ± 200	NS		1,100 ± 250	NS		5
Anti-TGF-β (d3–d7)		1,700 ± 100			2,000 ± 300			5

Quantification of the number of endocrine and exocrine cells developed in the pancreatic rudiments grown in vitro. The absolute number of endocrine and exocrine cells developed in the pancreatic rudiments was determined by counting respectively the number of endocrine cells (insulin- and glucagon-immunoreactive cells) and the number of exocrine cells (amylase-immunoreactive cells). The data represent the mean ± SEM. n = number of pancreatic rudiments analyzed per experience.