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. 2007 Dec 14;28(5):798–809. doi: 10.1016/j.molcel.2007.09.020

Figure 3.

Figure 3

USP1 Contributes to DNA Damage Tolerance

(A) Cellular sensitivity to DNA-damaging agents as determined by colony survival assay. The top left shows cisplatin, and the top right shows mitomycin C (MMC). The bottom left shows UV, and the bottom right shows X-rays. Error bars represent one standard deviation (SD).

(B) Propidium iodide cell-cycle analysis of wild-type DT40 and ΔUSP1 after exposure to different doses of cisplatin for 12 or 24 hr. 2N represents the G1 peak and 4N represents the G2/M peak.