Table 3.
Empirical power and false-positive rate when two unlinked regions are in LD with disease alleles
| Model | Forest |
FAMHAP* |
|||
|---|---|---|---|---|---|
| Power† | Power‡ | FPR§ | Power¶ | Power‖ | |
| Ep-1 | 0.995 | 0.695 | 0.035 | 1.000 | 0.010 |
| Ep-2 | 1.000 | 0.840 | 0.015 | 1.000 | 0.000 |
| Ep-3 | 1.000 | 1.000 | 0.002 | 1.000 | 0.000 |
| Ep-4 | 1.000 | 0.838 | 0.008 | 1.000 | 0.000 |
| Ep-5 | 1.000 | 0.982 | 0.017 | 1.000 | 0.000 |
| Ep-6 | 1.000 | 1.000 | 0.000 | 1.000 | 0.002 |
| Het-1 | 0.977 | 0.363 | 0.040 | 1.000 | 0.163 |
| Het-2 | 1.000 | 0.795 | 0.007 | 1.000 | 0.050 |
| Het-3 | 1.000 | 1.000 | 0.000 | 1.000 | 0.002 |
| S-1 | 0.967 | 0.347 | 0.037 | 0.998 | 0.213 |
| S-2 | 0.995 | 0.013 | 0.035 | 0.998 | 0.002 |
| S-3 | 1.000 | 0.895 | 0.013 | 1.000 | 0.003 |
| Ad-1 | 0.993 | 0.560 | 0.028 | 0.998 | 0.027 |
| Ad-2 | 0.970 | 0.187 | 0.033 | 0.995 | 0.158 |
*False-positive rate is not available.
†φ 1 = P (identify at least one correct haplotype).
‡φ 2 = P (identify both haplotypes correctly)
§False-positive rate.
¶φ 4 = P (identify at least a SNP in one region).
‖φ 5 = P (identify at least a SNP in each of the two regions).