Table 4.
Empirical power and false-positive rate when only one of the two unlinked regions is in LD with disease alleles
| Model | Forest |
FAMHAP |
||
|---|---|---|---|---|
| Power | False-positive rate | Power* | False-positive rate† | |
| Ep-1 | 0.973 | 0.032 | 0.998 | 0.088 |
| Ep-2 | 1.000 | 0.002 | 0.998 | 0.018 |
| Ep-3 | 1.000 | 0.003 | 1.000 | 0.003 |
| Ep-4 | 0.980 | 0.008 | 0.975 | 0.183 |
| Ep-5 | 1.000 | 0.005 | 0.998 | 0.015 |
| Ep-6 | 0.998 | 0.007 | 0.997 | 0.093 |
| Het-1 | 0.887 | 0.060 | 0.968 | 0.232 |
| Het-2 | 0.998 | 0.002 | 0.998 | 0.118 |
| Het-3 | 1.000 | 0.002 | 0.998 | 0.080 |
| S-1 | 0.883 | 0.047 | 0.968 | 0.250 |
| S-2 | 0.143 | 0.053 | 0.128 | 0.078 |
| S-3 | 0.992 | 0.013 | 0.997 | 0.083 |
| Ad-1 | 0.970 | 0.020 | 0.955 | 0.175 |
| Ad-2 | 0.782 | 0.058 | 0.880 | 0.270 |
*φ6 = P (identify at least a SNP in the region in LD with disease alleles).
†FP2 = P (identify at least a SNP in a neutral region).