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Three injections of PEGLA block blastocyst implantation in mice
| Treatment | n | Implantation sites | Corpora lutea |
|---|---|---|---|
| PEGLA | 5 | 0.0 ± 0.0* | 5.8 ± 0.7 |
| Control | 4 | 8.8 ± 0.5 | 7.8 ± 0.9 |
PEGLA or control (mPEG2-NHS) was administered to mated mice by i.p. injection (12.5 mg/kg) at 1200 hours and 2200 hours on D2.5 and 1000 hours on D3.5. Numbers of implantation sites and CL were recorded on D6.5. Data represent the mean number of implantation sites or CL per mouse ± SEM.
*, P = 0.0004 vs. control.
