Skip to main content
. 2007 Dec 5;104(50):19819–19824. doi: 10.1073/pnas.0709915104

Fig. 1.

Fig. 1.

Examples of the localized frustration and minimally frustrated networks in protein structures. The protein backbone, direct interresidue interactions, and water-mediated interactions are displayed as blue ribbons, solid lines, and dashed lines, respectively. Minimally frustrated interactions and highly frustrated ones are shown in green and red, respectively; neutral contacts are not drawn. The surfaces indicate the single-residue-level frustration index, using a corresponding coloring scheme. (A) Im7 protein [Protein Data Bank (PDB) ID code 7CEI] mutational frustration index. (B) Configurational frustration index. (C–E) Single-residue frustration index surfaces overlaid. (F–I) Configurational frustration index of IκBα (PDB ID code 1NFI) (F), Streptomyces Endoglucanase (PDB ID code 1OA4) (G), dihydrofolate reductase (PDB ID code 1RX2) (H), and Endostatin (PDB ID code 1KOE) (I).