Fig. 2.

Superimposition of the models for phosphorylated intermediate analogs fitted with the M7–M10 helices. Helices are represented with cylinders with marker residues in stick. The colors used are yellow, E2·BeF₃⁻(−TG); orange, E1·AlF₄⁻·ADP; and blue gray, E2·AlF₄⁻(TG). Small arrows show movements in the transition from E1P → E2P (a) and E2P → E2∼P (b). The TG binding site is indicated with an inverted triangle (b).