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Vacuolation of HeLa cells in response to water extracts of H. pylori. SPM 326 (open-square), H. pylori SPM 326vacA∷Km (open-circle), or H. pylori 95–54 (closed-square) as determined by the neutral red uptake assay. The insert shows an immunoblot of VacA in the water extracts of H. pylori SPM 326 (lane a) or 95–54 (lane b).
