Figure 5.

Immunofluorescence patterns of integrins in vivo and in vitro. Integrin expression patterns were examined by immunofluorescence microscopy in wild-type (A–D and I–L) and α3-deficient (E–H and M–P) skin sections (A–H) and in keratinocytes grown in culture (I–P). Immunofluorescence staining of α3 (A, E, I, and M), αv (B, F, J, and N), β1 (C, G, K, and O), and β4 (D, H, L, and P). Apart from the loss of α3, the staining patterns for other integrins in the α3-deficient skin and cells were normal. Bars: (H) 100 μm; (P) 10 μm.