Table 3.
Clinical features of patients with JAK2 mutations
| A. Subjects classified as PV | ||||||
|---|---|---|---|---|---|---|
| Patient | JAK2 lesion | Age at diagnosis/Gender | Disease duration (years) | White cell count (K/cu mm) | Platelet count (K/cu mm) | Palpable splenomegaly |
|
| ||||||
| PV1 | R541-E543delinsK | 61/M | 1 | 6.7 | 579 | 1 cm |
| PV2 | R541-E543delinsK | 50/F | 5 | 7.8 | 303 | 2 cm |
| PV3 | H538-K539delinsL | 18/M | 54 | 11.0 | 60 | massive |
|
| ||||||
| B. Subjects classified as idiopathic erythrocytosis | ||||||
| Patient | JAK2 lesion | Age at diagnosis/Gender | Disease duration (years) | White cell count (K/cu mm) | Platelet count (K/cu mm) | Palpable splenomegaly |
|
| ||||||
| ERT1 | N542-E543del | 54/F | 15 | 8.5 | 257 | none |
| ERT2 | R541-E543delinsK | 15/M | 1 | 5.8 | 291 | none |
| ERT3 | JAK2 V617F | 41/F | 1 | 5.7 | 227 | none |
| ERT4 | JAK2 V617F | 82/F | 10 | 6.9 | 111 | none |