Table 4.
Clinical features of patients with erythrocytosis
| A. Subjects classified as idiopathic erythrocytosis | ||
|---|---|---|
| JAK2 lesion-negative ERT
N= 40 |
JAK2 lesion-positive ERT
N= 8* |
|
|
| ||
| % female | 35% | 75% |
| Median age at diagnosis (range) | 49 (18-74) | 41(15-82) |
| Palpable splenomegaly | 0% | 0% |
| White cell count (K/cu mm) | 6.9 (4.2-14.7) | 6.4 (5.1-8.6) |
| Platelet count (K/cu mm) | 227 (109-753) | 285 (111-308) |
|
| ||
| B. Subjects with erythrocytosis and a JAK2 lesion | ||
| JAK2 V617F-positive PV or ERT
N= 149 |
JAK2 exon12 lesions PV or ERT
N= 15* |
|
|
| ||
| % female | 61% | 53% |
| Median age at diagnosis (range) | 49 (18-74) | 50 (15-62) |
| Palpable splenomegaly | 43% | 40% |
| White cell count (K/cu mm) | 11.9 (3.6-98.4)§ | 7.8 (6.7-12.1)§ |
| Platelet count (K/cu mm) | 507 (18-1320)# | 298 (60-579) # |