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. 1999 Aug 9;146(3):621–630. doi: 10.1083/jcb.146.3.621

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© 1999 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Differential expression of RyR1 and RyR3 in D25 diaphragm muscle. Longitudinal and cross-sections of D25 mouse diaphragm muscle were immunolabeled with antibodies against RyR1 (a and c) and RyR3 (b and d). Anti-RyR1 stains all muscle fibers, but anti-RyR3 stains only a fraction of the muscle fibers at this developmental stage. Serial sections (c and d) show that the fiber that expresses RyR3 (d) also contains RyR1 (c). Bar, 10 mm.