. Author manuscript; available in PMC: 2007 Dec 20.

Published in final edited form as: Neurosci Biobehav Rev. 2007 Apr 13;31(6):932–962. doi: 10.1016/j.neubiorev.2007.04.002

Table 5.

Studies of the effect of lithium on neuroleptic-induced behavioral supersensitivity.

Species, strain	Lithium	Experimental design	Results	Reference
Rat, SD	Li chow	Daily HAL i.p., then OFT	HAL-treated animals showed HyA, which lithium decreased	(Pert et al., 1978)
Rat, SD	Li i.p.	HAL i.p., then OFT	HAL-treated animals showed sedation, which lithium decreased	(Verimer et al., 1980)

Abbreviations: HAL: haloperidol; HyA: hyperactivity; i.p.: intraperitoneally; Li: lithium; OFT: open field test; SD: Sprague-Dawley.