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. 2000 Dec 25;151(7):1591–1598. doi: 10.1083/jcb.151.7.1591

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Identification of the hSTBP activity. (a) Proteins obtained from human sperm nuclei by extraction with high-salt or nonionic detergent were assayed for telomere binding using gel shift with the [TTAGGG]₁₂ probe. (b) Transition between low and high mobility hSTBP-[TTAGGG]₁₂ complexes induced by an increased concentration of nonspecific competitor DNA in binding reaction.