Figure 6.
Inhibition of p38 activation perturbs cytokinesis on one side of the blastomere. (A) BrdU staining of WT-p38aRNA–injected (125 pg) embryo. (B) Phalloidin staining of A. (C) Merged view of A and B. (D) BrdU staining of DN-p38a RNA–injected(125 pg) embryo. (E) Phalloidin staining of D. (F) Merged view of D and E. Cleavage furrow only formed on one side of the DN-p38a RNA–injected embryos (arrows) because of an incomplete mitotic segregation or cytokinesis on another side of the blastomere (arrowhead). Bar, 100 μm.
