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. 2000 Sep 18;150(6):1445–1460. doi: 10.1083/jcb.150.6.1445

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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FN expression pattern in the developing human pancreas. Confocal images of two adjacent microscopic fields (A and B) from cryostat sections stained for FN (green), insulin (blue), and PECAM-1 (red). A strong FN-specific immune reactivity (green) highlights the basal membrane of ducts (asterisk) and of insulin-positive cells (blue) emerging from the ductal epithelium (arrowheads, B and inset). The PECAM-1-specific staining (red), identifying blood vessels, reveals that the basal membrane of endothelial cells, infiltrating developing islet clusters, is also marked by a bright FN-specific staining (arrows). Bar, 100 μm.