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. 2001 Oct 1;155(1):65–76. doi: 10.1083/jcb.200106025

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Copyright © 2001, The Rockefeller University Press

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Figure 8. — Morphology of growth cones in cultured hippocampal pyramidal neurons. (A–M) Cells were double labeled with phalloidin (green) and a monoclonal antibody against tyrosine tubulin TUB-1A2 (red). Examples of bundled (A–D), spread (E-H), and looped (I-L) MTs in the growth cones after 2 d of culture of neurons from each genotype are shown. (M) Example of the abnormal cytoskeletal mass of growth cones from 8-d-old cultured neurons of map2 ^−/−map1b ^−/− mice. (N and O) Histograms of the percentages of three types of MT organization of the growth cones in axons (N) and minor processes (O).