Table 2.
Intrinsic and AP properties for SDH neurones grouped according to discharge pattern
| Sample | Tonic firing (TF) | Initial bursting (IB) | Delayed firing (DF) | Single spiking (SS) | Reluctant firing (RF) | |
|---|---|---|---|---|---|---|
| % of sample (n) | 100% (43) | 19% (8) | 25% (11) | 21% (9) | 23% (10) | 12% (5) |
| Input Resistance (MΩ) | 367 ± 21 | 385 ± 61 | 342 ± 51 | 380 ± 26 | 356 ± 34 | 388 ± 83 |
| RMP (mV) | −66.1 ± 1.1 | −62 ± 1.4 | −62.2 ± 1.7 | −69.2 ± 2.6 | −70.5 ± 2.6 | −70.5 ± 3.1 |
| Rheobase Current (pA) | 116 ± 18 | 25 ± 3 | 40 ± 5 | 128 ± 26 | 262 ± 27 | — |
| *DF and SS | *DF and SS | *TF, IB and SS | *TF, IB and DF | |||
| AP Threshold (mV) | −37.9 ± 0.6 | −39.6 ± 1.4 | −40.4 ± 0.7 | −34.6 ± 1.0 | −36.5 ± 1.3 | — |
| *DF | *DF | *TF & IB | ||||
| AP amplitude (mV) | 48.3 ± 1.6 | 55.9 ± 3.2 | 48.2 ± 2.4 | 43.0 ± 3.6 | 47.1 ± 3.6 | — |
| AP base width (ms) | 1.76 ± 0.06 | 1.58 ± 0.07 | 1.91 ± 0.12 | 1.92 ± 0.18 | 1.61 ± 0.09 | — |
| AHP amplitude (mV) | −30.5 ± 1.2 | −35.1 ± 1.6 | −29.6 ± 1.8 | −28.9 ± 0.8 | −29.2 ± 1.1 | — |
Values are means ± s.e.m. Membrane potential values are corrected for a 10 mV liquid junction potential (Barry & Lynch, 1991). AP properties could not be analysed in reluctant-firing neurones.
*
Significant difference (P < 0.05) and discharge categories compared.