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. 2006 Nov 30;578(Pt 3):819–829. doi: 10.1113/jphysiol.2006.120170

Figure 1.

Figure 1

APD shortening after switching the extracellular solution from Hepes to HCO3-buffered solution A, AP recordings under current-clamp mode before (Hepes) and after 1, 2, 5 and 10 min of superfusion of a cat ventricular myocyte with external HCO3. The presence of HCO3 in the external solution produced a gradual APD shortening. B, typical time course of beat-to-beat APD50 measured before and after switching the extracellular solution from Hepes to HCO3.