TABLE 4.

Structures of compounds prepared; inhibition of recombinant SQS for compounds of series 5; activities against L. mexicana promastigotes, axenic L. donovani amastigotes, and L-6 cells; and effects on the sterol compositions of L. mexicana promastigotes^a

^aSee footnote a of Table 1 for explanations and the definitions of the abbreviations. The IC₅₀s for human SQS were not determined. Et, ethyl; Ph, phenyl.