Figure 6.
Effect of PTX on K+-evoked calcium increases in Sol cell lines. (A) Representative examples of K+-evoked calcium increase in a SolC1(−) in control conditions and in the presence of PTX (+PTX, 1 μg/ml). Histograms representing the amplitude (ΔF/F0) (B) in SolC1(−) (white bars) and SolD(+) (black bars), the “area under the curve” parameter (C), time to peak (s) (D), increase slope (E), and half decay (F) in controls and with PTX exposure. The number of analyzed myotubes is given on histogram bars in B. ns, not significantly different. ***, P < 0,001; **, 0.001 ≤ P < 0.01; *, 0.01 ≤ P < 0.05 (Student's unpaired t test).