TABLE I.
pH50 of Steady-state Desensitization and Activation
| ASIC1a | C43 | C62 | C92 | C98 | C166 | ASIC1b | |
|---|---|---|---|---|---|---|---|
| pH50 (SSD) | 7.19 ± 0.01 (8) | 7.26 ± 0.01 (6) | 7.23 ± 0.09 (8) | 7.17 ± 0.13 (8) | 7.02 ± 0.02 (9) | 6.90 ± 0.01 (5) | 6.95 ± 0.03 (6) |
| pH50 (Act) | 6.56 ± 0.04 (7) | 6.00 ± 0.11 (6) | 6.78 ± 0.06 (9) | 6.77 ± 0.08 (6) | 6.32 ± 0.07 (10) | 6.07 ± 0.05 (7) | 5.70 ± 0.04 (7) |
Data are mean ± SD for the number n of individual oocytes indicated in brackets. Data for ASIC1a are from Chen et al. (2005) and data for C62, C92, and C98 are from Babini et al. (2002). SSD, steady-state desensitization; Act, activation.