Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Aug;128(2):171–184. doi: 10.1085/jgp.200609555

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — Shift of the dynamic range. Current responses induced by photolysis of caged 8-Br-cAMP in two olfactory sensory neurons. Currents were measured as a function of relative flash intensities in control and in adapted condition for the first (A–D) and the second (E–H) olfactory neuron, respectively. Relative flash intensities were 0.32, 0.50, and 1 in the first neuron (A and B), with I_max = −1150 pA, and 0.1, 0.5, 0.8, and 1 in the second neuron (E and F), with I_max = −340 pA. The superimposed current responses in the adapted state were obtained from the experiments illustrated in C and G: an adapting flash of maximal light intensity was applied to the neuron followed by a second flash after 19 s in C and 30 s in G. The intensity of the first flash was kept constant and the intensity of the second flash was varied as indicated in the figure. The holding potential was −50 mV. (D and H) Normalized peak currents were plotted versus relative flash intensity both for the control (filled squares) and for the adapted (open squares) state. Data were fitted by the Hill equation, Eq. 1, with F_1/2 = 0.36 and n = 3.7 in the control, and with F_1/2 = 0.85 and n = 5.5 in the adapted state for the first neuron (D), and with F_1/2 = 0.11 and n = 3.2 in the control, and with F_1/2 = 0.72 and n = 1.9 in the adapted state for the second neuron (H). Results showing a shift of the dynamic range in the adapted state toward higher light intensities compared with the control state were measured in three olfactory sensory neurons.